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Clinical Evidence

This is where you’ll find all of the latest clinical evidence surrounding Xelma’s efficacy in wound care – in theory and in practice. Use the drop-down menu to access published papers and detailed case studies featuring the real experiences of patients and professionals.

This section will be constantly updated to bring you the latest and most relevant research findings.

  • Clinical Studies
  • Pre Clinical Studies
  • Case Reports

Use the drop down menu above to view the relevant studies and reports


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How Xelma works

When applied to the wound bed Xelma restores the damaged proteins providing an extracellular matrix protien for cell attachment.
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Pre-clinical data

Pre-clinical studies demonstrated that amelogenin treatment significantly increases fibroblast expression of vascular endothelial growth factor (VEGF), a growth factor that plays an important role in wound healing.
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How to use Xelma

Xelma is indicated for hard-to-heal ulcers - primarliy, venous leg ulcers. Xelma can be used under compression therapy.
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