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This is how Xelma Works

In hard to heal wounds the extraceullular matrix (ECM) is degraded resulting in a reduction in cell proliferation and secretion of growth factors.

When applied to the wound bed Xelma restores the damaged proteins providing an extracellular matrix protien for cell attachment.

This creates favourable conditions for wound healing by restoring vital cell functions including proliferation, migration and production of growth factors and essential extracellular matrix components.

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A novel treatment

Xelma® is a novel treatment for hard-to-heal wounds without clinical signs of infection such as venous leg ulcers, diabetic foot ulcers and pressure ulcers.
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Pre-clinical data

Pre-clinical studies demonstrated that amelogenin treatment significantly increases fibroblast expression of vascular endothelial growth factor (VEGF), a growth factor that plays an important role in wound healing.
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How to use Xelma

Xelma is indicated for hard-to-heal ulcers - primarliy, venous leg ulcers. Xelma can be used under compression therapy.
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